TIP307


Course Title Course Code Program Level
DEPARTMENT OF PHARMACOLOGY TIP307 Medicine B.A. / B.Sc.

Course Term
(Course Semester)
Teaching and Learning Methods
Credits
Theory Practice Lab Projects/Field Work Seminars/Workshops Other Total Credits ECTS Credits
05
(Fall)
144 144 4 5

Teaching Staff Doç. Dr. M. Devrim Güner, Yrd. Doç. Dr. Şahika Güner
Language of Instruction Türkçe (Turkish)
Type Of Course Compulsory
Prerequisites -
Recommended Optional Programme Component
Course Objectives To teach pharmacokinetic and pharmacodynamic principles of pharmacological agents in accordance with rational drug use and with a modern and contemporary approach,
Course Content Introduction of pharmacological characteristics and functions of drugs under each clinical subtitle.
Learning Outcomes (LO) LO1-Learns the definition of pharmacological concepts, pharmacokinetics and pharmacodynamics definitions and relates to therapeutics used in clinical practice. LO2-Learns the mechanisms and location of drug action and routes of drug administration and relates to pathological and physiological conditions. LO3-Defines and correlates the clinical outcomes of adverse drug reactions and drug interactions. Knows the process of adverse drug reaction reporting. LO4-Defines and learns the clinical importance of pharmacogenomics, pharmacoeconomics and pharmacoepidemiological approaches. LO5-Learns the differences in pharmacological approaches to special patient groups (pediatric, geriatric, pregnant etc.) Defines the effect of these conditions on drug activity and knows how to use this information in clinical practice LO6-Knows phases of drug development, clinical research and ethical considerations in pharmacological research. LO7- Defines the drug and patient related factors that affect the activity of drugs LO8- Learns the definitions and importance of bioavailability, bioequivalence, drug compliance in clinical practice. LO9-Knows the importance of each clinical condition and disease in planning and performing of treatment and drug choice. Plans the appropriate treatment regimen. LO10-Learns rational drug use and knows the importance and application of it in clinical practice LO11-Gains the ability of writing accurate and specific prescription for each patient and disease after diagnosis. LO12-Values to have a full command of pharmacological knowledge and importance of scientific and ethical approach in clinical practice; knows the importance and value of being a physician with these abilities.
Mode of Delivery Face to face
Course Outline
Week Topics
1. Week Introduction to pharmacology, formulations, routes of administration Pharmacokinetics: Absorption-Distribution and Elimination
2. Week Dose-concentration response, biotransformation, pharmacokinetic interactions
3. Week Receptor theory, drug – receptor interactions, pharmacodynamics Mechanism of action, and pharmacodynamics interactions
4. Week Toxicology Pharmacogenomics and effect on drug actions
5. Week Autonomic Nervous System and pharmacological agents that effect ANS
6. Week Parasympathomimetic and parasympatholytic agents
7. Week Sympathomimetic and sympatholytic drugs
8. Week Autacoids, histamine and antihistamines Serotonin & Ergot Alkaloids
9. Week Vasoactive Peptides Arachidonic acid metabolites & Nitric oxide
10. Week Respiratory system pharmacology Treatment of asthma
11. Week Nonsteroidal anti-inflammatory drugs
12. Week Opioid analgesics and Antagonists Muscle relaxants
13. Week Vitamins- 1. Mid –term exam
14. Week Gastrointestinal system pharmacology
15. Week Cardiovascular system pharmacology
16. Week Treatment of congestive heart failure
17. Week Antihypertensive drugs
18. Week Antianginal drugs, antiarrhythmic drugs
19. Week Coagulation , anticoagulation Hematopoietic system pharmacology
20. Week Hypolipidemic drugs
21. Week Endocrine system pharmacology, Hypothalamic and pituitary hormones
22. Week Estrogens, Progestin and posterior pituitary hormones Androgens
23. Week Growth factors and related drugs, Agents affecting mineral ion homeostasis and bone turnover
24. Week Pancreatic Hormones and hypoglycemic drugs Thyroid Hormones and related drugs
25. Week Adrenal cortex and Adrenocortical steroids, antagonists 2. Mid –term exam
26. Week Central nervous system pharmacology
27. Week Sedative hypnotic drugs General and Local Anesthetics,,
28. Week Alcohol and addiction, drug abuse Antidepressants, Anxiolytics drugs CNS stimulants
29. Week Antipsychotic drugs
30. Week Antiepileptic drugs, treatment of CNS degenerative diseases Treatment of Alzheimer and Parkinson Disease
31. Week Introduction to antibiotics, Rational antibiotic therapy
32. Week Cell wall synthesis inhibitor, Penicillin& cephalosporins Monobactams& Beta-Lactamase inhibitors & Carbapenem & Glycoopeptid Antibiotics Aminoglycosides ve Spectinomycin & Sulfonamides, Trimethoprim and Quinolones
33. Week Protein synthesis inhibitors; Macrolides, Tetrasiklin, Lincosamidechloramphenicol, Streptogramins, Oxazolidinediones Antifungals and Antituberculosis medications
34. Week Antivirals; Antiretrovirals & Protease Inhibitors Antiseptics, Disinfectants, Sterilants Antiprotozoal drugs; treatment of malaria and amebiasis Antihelmentics
35. Week Cancer Chemotherapy and Antineoplastic drugs Immunopharmacology & drugs affecting immune system
36. Week Pediatric, Geriatric Clinical Pharmacology Drug use in Perinatal, and pregnancy period
37. Week Rational Pharmacotherapy and prescription rules 3. Mid-term exam
38. Week
Assessment
  Percentage(%)
Mid-term (%) 40
Quizes (%)
Homeworks/Term papers (%)
Practice (%)
Labs (%)
Projects/Field Work (%)
Seminars/Workshops (%)
Final (%) 60
Other (%)
Total(%) 100
Course Book (s) and/or References 1. Basic and Clinical Pharmacology (Bertram Katzung, Masters, Trevor. LANGE), 2. Lippincott's Illustrated Reviews: Pharmacology (R.A. Harvey, P.C. Champe, Lippincott Williams & Wilkins), 3. The Pharmacological Basis of Therapeutics. Goodman & Gilmans. Laurence Bruton, Bruce Chabner, Bjorn Knollman, 4. KAYAALP Tıbbi Farmakoloji, (Prof.Dr. Oguz KAYAALP)
Work Placement(s)
The Relationship between Program Qualifications (PQ) and Course Learning Outcomes (LO)

 

PQ1

PQ2

PQ3

PQ4

PQ5

PQ6

PQ7

PQ8

PQ9

PQ10

PQ11

PQ12

PQ13

PQ14

PQ15

PQ16

PQ17

LO1

2

2

2

5

2

1

1

1

1

1

1

5

2

1

1

1

1

LO2

4

2

1

5

5

1

1

1

1

1

1

5

2

1

1

1

1

LO3

1

5

5

5

5

1

3

5

5

4

1

5

2

1

5

5

5

LO4

4

5

5

5

3

1

3

3

1

3

1

2

2

1

1

1

1

LO5

3

5

5

5

5

1

4

1

1

5

1

2

2

1

5

1

1

LO6

1

1

1

5

3

1

4

1

3

1

1

5

5

1

1

1

1

LO7

3

4

4

5

3

1

2

3

1

4

1

2

2

1

5

1

1

LO8

1

3

3

5

5

1

5

3

1

4

1

4

2

1

5

1

1

LO9

3

5

5

5

5

1

5

5

3

5

1

4

4

1

5

5

5

LO10

2

2

2

5

5

1

5

5

1

5

1

4

4

1

5

5

5

LO11

1

2

2

5

5

1

5

5

5

5

1

4

4

1

5

5

5

LO12

1

2

2

5

5

1

5

5

5

5

1

4

4

1

5

5

5