| Teaching Staff
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| Language of Instruction |
Türkçe (Turkish) |
| Type Of Course |
Compulsory |
| Prerequisites |
None |
| Recommended Optional Programme Component |
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| Course Objectives |
The principal aim of this course is teaching the basic molecular and genetic terminology and human genetic concepts to the students in order to equip them for their future medical carriers. Another objective of the course is to provide enough knowledge to the students about genetic diseases and their inheritance, prenatal and postnatal diagnostic tools, understanding the principles of molecular and genetic techniques that are used in diagnosis and research and also interpretations of the results of these tests. |
| Course Content |
In this course, students will gain teoretical and practical understanding of the importance of genetics and molecular biology in Medicine. Course will cover structure of genes and chromosomes, cytogenetics, molecular cytogenetics, techniques in molecular biology , common single-gene disorders, Mendelian inheritance patterns, autosomal inheritance and diseases, disorders of gonadal and sexual development, , mitosis and meiosis, prenatal and postnatal diagnostic tecniques and ethical issues in medical genetics. |
| Learning Outcomes (LO) |
|
| Mode of Delivery |
Face to face |
| Course Outline |
| Week |
Topics |
| 1. Week |
Genetics in Medicine |
| 2. Week |
Mitotic Cell |
| 3. Week |
Meiotic Cell Division |
| 4. Week |
Numerical chromosomal abnormalities |
| 5. Week |
Structural chromosomal abnormalities |
| 6. Week |
Inheritance Patterns: Autosomal dominant inheritance |
| 7. Week |
Inheritance Patterns: Autosomal recessive inheritance |
| 8. Week |
Inheritance Patterns: X-linked inheritance |
| 9. Week |
UPD, Imprinting, Triplet repeat disorders |
| 10. Week |
Mitochondrial inheritance |
| 11. Week |
Lessons from the hemoglobinopathies |
| 12. Week |
Molecular basis of genetic diseases I |
| 13. Week |
Molecular basis of genetic diseases II |
| 14. Week |
Genetics of the İmmune system |
|
| Assessment |
| |
Percentage(%) |
| Mid-term (%) |
40 |
| Quizes (%) |
|
| Homeworks/Term papers (%) |
|
| Practice (%) |
|
| Labs (%) |
|
| Projects/Field Work (%) |
|
| Seminars/Workshops (%) |
20 |
| Final (%) |
40 |
| Other (%) |
|
| Total(%) |
100 |
|
| Course Book (s) and/or References |
1-Hücrenin Moleküler Biyolojisi, Garland Science, TÜBA, 4. Baskı, B. Alberts, A. Johnson, J Lewis, M Raff, K Roberts, P Walter. , 2008
2- Tıbbi Biyoloji ve Genetik, Nobel Kitabevi, Prof.Dr.Halil Kasap (Editör), 2010
3- Thompson & Thompson Genetics in Medicine, 6th Edition Robert L. Nussbaum, Robert L. Nussbaum Roderick R. McInnes, Huntington F. Willard 2009
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| Work Placement(s) |
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| The Relationship between Program Qualifications (PQ) and Course Learning Outcomes (LO) |
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